Omega-3-acid Ethyl Esters Gelcaps (Generic Lovaza)

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Drug information on Omega-3-acid Ethyl Esters (Generic Lovaza)

How to Use and Dosage

Omega-3 Acid Ethyl Esters gel caps are oral medicines with the generic brand name Lovaza. Lovaza is a lipid-regulating (antilipemic) agent that is supplied as a gel capsule. It is an oral medication. A capsule of Lovaza is available in one gram. Each capsule of this medicine contains at least 900 milligrams of the lipid-regulating ethyl esters of omega-3 fatty acids. The predominant ethyl esters constituents include docosahexaenoic acid (DHA), which is approximately 375 milligram and eicosapentaenoic acid (EPA), which is approximately 465 milligram. The active ingredients of this medicine include gelatin, alpha-tocopherol, and glycerol with purified water.

This medication is used along with diet to reduce the levels of triglyceride (a fat-carrying agent) in the blood of adult patients that have high levels of triglycerides. High levels of triglycerides in the blood are associated with complicated health conditions, such as diabetes mellitus and obesity. It also contributes to the risk of atherosclerosis, hardening of the arteries). The known mode of action by which Lovaza gets rid of these health issues is by lowering the triglycerides that are produced by the liver and raises the good cholesterol (HDL, High-density lipoproteins) level in the blood.

Lovaza is used when treatments, such as diet plans, exercise, abstaining from alcohol, weight loss regimens, sugar intake control (if diabetic) and regulation of thyroid hormone levels fail. Omega-3 acid ethyl esters help to decrease the risk of strokes and prevent myocardial reinfarction.

In order to use Omega-3 acid ethyl esters, take it orally with food or without food, but more importantly, as directed by your doctor. It is usually used once or twice in a day. You will have to swallow the whole capsules. The capsule is dissolved, crushed or chewed while taking it. Use the drugs regularly, but the dosage should be based on your health conditions and your response to the treatment with the drugs. However, you need to follow your doctor's prescriptions and directions as regards diet and exercise.

Lovaza daily dose is dose is 4 grams in a day. This 4-gram daily dose may be taken at once by taking 4 capsules or twice in a day by taking 2 capsules each time. Ultimately, follow your doctor's instructions.

Side Effects

Omega-3 acid ethyl esters are accompanied by side effects. The common side effects are stomach upset, burping, dry mouth and unusual taste in the mouth, back pain, skin rash, loss of appetite, constipation, diarrhea and back pain.

Serious side effects that you need to see your doctor right away for include bruising and bleeding, vomit that has the look of coffee grounds, and black or tarry stool. The serious allergic reactions that may be noticed while taking this drug include itching and swelling of the face, tongue, lips and tongue; severe dizziness, hive, and difficulty in breathing. Nevertheless, these serious allergic reactions to the medication are rare. Side effects and allergic reactions vary and they depend on individual physiology. So the list above is not a complete list of all the side effects that you are likely to experience while taking Lovaza, but if you notice any of these or any other ones not listed, contact your doctor immediately.


If you noticed that you are allergic to some diets like fish, soy products, shellfish or if you have any other allergies, see your doctor and discuss your allergic conditions before taking Omega-3 acid ethyl esters. This is due to the fact that this drug may contain some inactive constituents that may trigger severe allergic reactions. So you need to talk to your doctor for medical advice. In addition, you need to tell your doctor your medical history. You have to give your doctor the information regarding your use of alcohol and your health conditions, whether you have diabetes, underactive thyroid (hypothyroid) or liver disease.  If surgery is recommended to you, before it is carried out, ensure that you tell your doctor or dentist about all the medications you have used, including prescribed and non-prescribed medications. Do not leave out any herbal products you have used.

For pregnant women, they will have to take this medicine when needed, but as prescribed by their physicians. If you are a nursing mother, you need to consult your doctor for advice before taking it because the medicine will pass into the breast milk. Aspartate aminotransferase (AST) and Aline aminotransferase (ALT) levels should be periodically monitored in patients with hepatic impairment while they are administering Lovaza. Moreover, the level of low-density cholesterol (LDL) should be monitored because some patients may experience an increase in the level of LDL while taking Lovaza.


Omega-3 acid ethyl esters interactions may increase the risk of developing severe side effects. The list of drugs that might counteract with this medication is yet to be confirmed, but medicines that can increase the level of triglycerides are more likely to counteract with Lovaza. These mediccines include estrogens, beta blockers, water pills, thiazides, vitamins, and supplements like fish oil, flaxseed oil and cod liver oil.

Clinical studies have shown that Lovaza is safe to be used with Simvastatin, Rosuvastatin, and Atorvastatin. Nonetheless, it is imperative that you consult your doctor before taking it with any medicine.

Do not change the dosage without your doctor’s approval.


An overdose of Omega-3 acid ethyl esters is more like to cause serious symptoms, such as breathing difficulty, internal bleeding, and the side effects listed above. The overdose may result in easy bleeding and bruising, gastrointestinal bleeding, bleeding in the brain - sign of hemorrhagic stroke, and severe headache. In order to avoid the overdose of Omega-3 acid ethyl esters, ensure that you strictly adhere to your doctor's prescription.

Keep the drug out of the reach of others, especially children. Do not share the medication with others. In spite of this, if someone has overdosed and serious symptoms begin to develop, call 911 or the poison control center. If you are a US resident, call the poison control center at 1-800-222-1222.

Omega-3-acid Ethyl Esters Gelcaps

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