Hydrochlorothiazide Tablets (Generic Microzide)

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Microzide is the brand name for the medication generically known as hydrochlorothiazide. It belongs to a class of drugs known as diuretics, meaning that it stimulates the body into getting rid of water, mainly through the creation of more urine which is then expelled from the bladder.

What is Microzide Used For?

Urine is composed mainly of water, salt, and other excess minerals, and thus the medical industry prescribes it to patients whose conditions would benefit from a reduction of these substances. Patients suffering from conditions such as liver cirrhosis, congestive heart failure, or kidney disorders will often experience edema, which is another name for fluid retention by the body. Edema can also come about as a side effect of taking hormones such as estrogen and steroids.

By influencing the kidneys to create more urine by absorbing more water and salt from the bloodstream, the drug will relieve a patient's water retention. An excessive amount of salt in the body is also a cause of hypertension or high blood pressure, and by taking away salt from the bloodstream in the urine creation process mentioned above, having a patient take a hydrochlorothiazide tablet can relieve the situation.


Microzide is taken orally as it comes in pill form, and the dosage will vary according to the severity of a patient's condition and other influencing factors such as how well a patient responds to the treatment. Most patients will be instructed to take one hydrochlorothiazide tablet a day, and the recommended time to do this is in the morning, whether or not you've had breakfast. The reason for this is that the pill will cause increased urination, which might interfere with your sleep if the pill is taken anything less than 4 hours before bedtime.

Should you feel that the prescribed dosage is not working well for you - report this to your doctor so that they may either adjust the dosage or reconsider the treatment method altogether.

Before taking Microzide, be sure to inform your doctor if you've been experiencing any other illness or condition that causes vomiting and/or diarrhea, as the loss of fluid these cause might have a bearing on your prescription.

Physicians will tell their patients what types of liquids they should be taking while under hydrochlorothiazide treatment, so be sure to pay attention and follow these instructions.

Never share your medication with other people, and should you miss a dose, simply take it the moment you remember. If you're close to the next scheduled dose, skip it. Don't take a double dose to 'catch up'.

As with all medication, hydrochlorothiazide should be taken in the exact dosage the prescribing doctor indicates. Safety should always be a patient's first priority. The prescription label will have all this information, and you shouldn't go above or below what's there, even if you feel better or worse.

Side Effects

Doctors will prescribe Microzide in cases where they think there will be little risk of serious side effects, meaning that most people will not experience any. However, there is the still a possibility.

Should you experience any of the following, get in touch with your doctor immediately.

  • Impaired eyesight or pain in the eyes
  • Dehydration, which is characterized by a very dry mouth, extreme thirst, irregular/slow/quickened heartbeats, decreased urination, confusion, and muscle cramps/weakness.
  • Serious allergic reactions, characterized by any of the following: itching, rashes, trouble breathing/chest tightness, severe dizziness, or swelling of the face, throat, and tongue region.
  • As your body adjusts to the medication, you may experience dizziness, headaches, or an upset stomach, and if these don't go away quickly or seem to get worse, you should let your doctor know.

Be sure to inform your doctor if you have any allergies or if you know you are allergic to hydrochlorothiazide itself.


As the drug might make you dizzy, taking marijuana or alcohol might worsen this. Avoid driving, operating machines, or any other activities that call for quick reactions and alertness until you feel safe doing so.

Be careful about staying out in the sun too long and avoid tanning booths and lamps as hydrochlorothiazide may increase your skin's sensitivity to them. Should blisters or sunburn occur, inform your doctor as soon a possible.

High-potassium foods such as oranges, bananas, and certain salt substitutes might help you avoid a drop in your potassium levels, which is a possibility while under this medication. If you prefer, ask your doctor about potassium supplements.

Older patients should be extra vigilant while using the drug, as they might be more susceptible to its effects, especially when it comes to dizziness.

Dehydration can come about as a result of vomiting, diarrhea, or excessive sweating while taking this medication, so drink plenty of fluids while taking it and report to your doctor if you experience any prolonged spells of these conditions.

Regular blood sugar checks should be undertaken by those with diabetes, as the drug might have an impact on your blood sugar levels. Be sure that your doctor is aware of your condition in advance.

Pregnant and nursing women should consult with their doctor about the advisability of using the drug. Even though it's unlikely to affect a breastfeeding baby, pregnant women should only take it if absolutely necessary.

Always store all your prescription medication away from children and pets somewhere away from heat, light, and excessive moisture (keep away from the bathroom).


When you take a hydrochlorothiazide tablet, there is the possibility that it may encounter another drug you might be taking, resulting in the lessened effectiveness of either drug or an increased risk of negative side effects.

Let your doctor know if you are taking any herbal products, prescription, and non-prescription medications and supplements before you start your course of Microzide:

  • Dofetilide
  • Lithium
  • Cough and cold medications
  • Dietary aids
  • Ibuprofen or naproxen

Should you have a lab test of any kind scheduled, make sure the lab personnel know as well as your doctor as this might interfere with the accuracy of certain tests such as that for parathyroid function.


An overdose may occur should someone take more than the prescribed dosage or if they have a serious reaction to the medication. Should you notice any of the warning signs including trouble breathing, loss of consciousness, bodily weakness, or severe dizziness, immediately call your nearest poison control center at 1-800-2221222 (US residents).

Hydrochlorothiazide Tablets

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