Apixaban: Review for Stroke

Apixaban, commonly referred to as Eliquis, is a prescription drug which acts as an anticoagulant to prevent or eliminate blood clots. It is effective at stroke management for people that have atrial fibrillation. The drug is specifically used in the prevention of blood clots for those with a history of such a problem or after one’s knee, or hip has been replaced. Its effectiveness in the elimination and prevention of blood clots has made it a drug of choice for treatment of Pulmonary Embolism and Deep Vein Thrombosis.

Method of Action and Dosage.

Apixaban directly acts on the clot-bond and free factor xa in a reversible manner. Since factor xa is the enzyme that enhances the production of thrombin from prothrombin, the mesh of thrombin normally evident as a clot is inhibited. The orally bioavailable medicine is highly selective in its work meaning that it only works on the enzyme and does not directly impact the segregation of platelets. The FDA approved drug indirectly causes a reduced rate of clot formation.

Eliquis for stroke should be taken as per the doctor’s prescription which is normally twice within a single day. The drug is actionable whether taken with or without food. It is normally available in two varying tablets which are:

A 2.5 mg tablet which is round in shape and pale yellow in color;

A 5 mg tablet which is oval in shape and pink or pale orange in color.

The tablets are inscribed each having the strength of the particular dosage on one of the sides and the medicine’s identification number on the other side. The ideal Apixaban dose described above should be followed strictly unless doctor advices otherwise.

What happens if you suddenly stop taking Apixaban for stroke?

Eliquis medication should be taken without failure. Stopping the Eliquis anticoagulant can lead to severe health consequences including a stroke at any time. However, there are certain cases that may necessitate one to stop taking the medicine. This includes serious scenarios like when one has to undergo surgery. It is important to consult the physician who gave the prescription before going off the medicine. The same is applicable for instances when one needs to undergo a dental or any other severe medical procedure.

When a dose is skipped, one should take it as soon as they remember without taking an additional Apixaban dose.

AJ (took for 6 months to a year) 9th March, 2019: “Great drug. MY life was saved after taking Apixaban. Diagnosed with acute DVT and PE later on in my right lung later on. I take 5mg twice per day. Blood pressure has lowered, and I can even use salt nowadays. Eliquis (Apixaban) for PE: Diagnosed with double Pulmonary Embolisms plus a clot inside both my heart and stomach and 1 DVT. I was 39 at the time. Initially, my doctor prescribed Xarelto but recommended Eliquis after I experienced hair loss. My platelet count has increased, and I have heard zero additional side effects.”

Side Effects

It is important to note that clots will take longer to form during bleeding when one is on the Eliquis medication. This should however not be a cause for alarm since there have never been serious conditions reported from such a scenario.  All drugs have side effects and the common minor impacts to be expected of Apixaban include: light chest tightness or aches, dizziness, skin rashes, and some light allergic reactions. It is important nonetheless to note that not all patients using Eliquis experience the side effects. The effects wear out also as soon as the blood and body adapt to the drug.  It is important to contact a doctor as soon as any of the above or other side effects are witnessed. The importance of consulting a doctor swiftly is because the majority of the side effects outlined can be caused by other aspects apart from Eliquis anticoagulant.

Eliquis can lead to minor bleeding which does not cause death and is on numerous occasions associated with a combination of the Apixaban dose with any of the following drugs: Aspirin, Heparin, selective serotonin, reuptake inhibitors, Warfarin, non-steroidal anti-inflammatory medicines, any other drugs taken for treatment or prevention of blood clots.

Patients who have any of the following should never use Eliquis: Synthetic heart valves; already experiencing abnormal bleeding, severe allergic reactions to Eliquis in the past.

Apixaban anticoagulant is a cost-effective means of managing conditions like Stroke, Pulmonary Embolism, or other blood clotting related conditions while also helping with post-surgery recovery. This is as compared to other options available for similar treatment like Warfarin. One should always take the full dosage without skipping as recommended by their doctor.

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