Mirapex or pramipexole 0.25 mg 30 tablet, synonymously known as pramipexole dihydrochloride is a treatment used to treat restless leg syndrome (RLS) and Parkinson disorder. The former is caused by the failure of the nervous system. The latter affects body movement hence causing a decrease in motion, muscle rigidity, and posture instability. Stimulation of the dopamine receptors which are located in the striatum is responsible for signals being sent from the thalamus to the cortex cerebral and to the spinal cord. An individual suffering from Parkinson's disorder experiences degeneration of substantia nigra and pars compacta which consequently causes a reduction in dopamine production. Due to this, dopamine receptors are not well stimulated therefore decreasing the signals sent from the thalamus to the spinal cord and the cerebral cortex.
Mirapex 0.25 dosage and how the drug should be taken
Parkinsonism disorder is prescribed two forms of tablets. These are the extended-release tablets and immediate- release tablets. For an individual suffering from Restless leg syndrome, he or she is prescribed to use immediate-release tablets. Mirapex 0.25 mg tablet or pramipexole 0.25 mg 30 tablet reverses the Parkinson disorder by combining with dopamine and the D3 receptors consequently encouraging effective stimulation in the dopamine receptors.
Individuals with Parkinson disorder are required to take the drug three times a day from the 30 tablets pack. Pramipexole 0.25 mg 30 tablet dosage increases weekly depending on the physician. The beginning dose is 0.125mg for the first week. Pramipexole 0.25 mg 30 tablet dosage progresses henceforth to 0.25mg, 0.5mg, 0.75mg, 1mg, 1.25mg and 1.5mg respectively up to the seventh week. The extended-release tablets are prescribed to be taken once daily. The beginning dose is 0.125mg and the maximum dosage is 4.5mg. The dosage can be increased after 5 or 7 days depending on the doctor’s instructions.
In the case of restless leg syndrome, pramipexole dihydrochloride 0.25mg is taken 2-3 hours before going to bed. An individual is required to take 0.125mg for the first week. The dosage of the 30 tablets pack can be increased up to 1.5mg as conditioned by the doctor.
Side effects of Mirapex 0.25 mg or pramipexole 0.25 mg 30 tablet
If prescribed to Mirapex 0.25 mg tablet, a patient may experience some side effects. Pramipexole 0.25 mg 30 tablet side effects include diarrhea, nausea, constipation, sleep disorder, and body weakness.
The most serious side effects include hallucinations, depression, and visual disturbances. In case one experiences these side effects, it is recommended that he or she stops taking the medication and consults the physician.
In case you have an allergy to the medication, it is advised that you make it known to your doctor before he or she prescribes the dosage.
Pramipexole 0.25 interaction
It is prohibited to use Mirapex 0.25 mg tablet with drugs that cause drowsiness. Moreover, muscle relaxers, codeine, tramadol, and morphine should not be used together with pramipexole dihydrochloride 0.25 mg.
The consumption of alcohol while taking this medication is also prohibited because it may cause an individual to be extremely drowsy.
Precautions to be taken when prescribed Mirapex 0.25 mg
The drug should be stored in a cool dry place and kept out of reach of children.
Pregnant women should only use pramipexole tablets 0.25 mg when the benefits have been established to be greater than the risk.
In a situation where you want to seize taking the medication due to various circumstances, it is proper that you consult a physician.
In case there is difficulty in swallowing the tablets whole, inform the doctor in order to get assistance.
If it happens that an individual has missed a dose, it is prudent that he or she informs the doctor for further directions.