Allopurinol Tablets (Generic Zyloprim)

by Europe

Allopurinol Tablets (Generic Zyloprim) is a pharmaceutical drug that reduces the production of uric acid in your body and is used to treat kidney stones or gout. It’s also used to treat infections, seizures, and pain caused by pancreas disease as well as to control the level of uric acid among cancer patients. The increase in uric levels among these patients can be attributed to the dying cancer cells in their bodies. It, therefore, works by reducing the amount of uric acid that can lead to kidney problems and gout.

Uses and Dosage

You need to take this medication orally once every day or as directed by your physician. However, in order to reduce stomach upset, take it after a meal.The adult initial dose is 100 to 200 mg. If your medical doctor recommends more than 300 grams you need to take several small doses during the day. With each dose, make sure you drink 1 full glass of water and at least 8 more glasses of fluid a day. Your doctor may advise you to drink less fluid or reduce the amount of acid in your urine. The dosage is basically depended on your response to the treatment and medical condition. To ensure that you are consistent, always take it at the same time.

If you are treating gout, you may need to take it for several weeks for it to have an effect. While the body removes uric acid, you may have more attacks after starting this medicine. But if your condition worsens or there is no change, inform your doctor.

Side effects

If you experience any of these side effects stop using the drug or call your doctor immediately.

  • Headache, fever, and sore throat.
  • Any initial sign of any skin rash.
  • Bleeding or pain when you urinate.
  • Upper stomach pain, nausea, weight loss, loss of appetite and jaundice.
  • Not urinating at all or urinating less than usual.
  • Flu symptoms and joint pains.
  • Numbness, severe tingling, muscle weakness, and pain.
  • Unusual bleeding and easy bruising.

Other less serious side effects that you may experience include diarrhea, vomiting, headache drowsiness, muscle pain, and changes in your sense of taste.


If you have ever had a severe allergic reaction to this drug, then do not take this medication. No matter how mild, if you have any signs of skin rash you need to call your doctor. It’s also important to tell your doctor about your medical history especially if you have ever suffered from diabetes, kidney disease, high blood pressure, and unusual diets.

Since this drug can make you drowsy avoid taking alcohol or marijuana while taking it. Do not use any machinery, drive or engage in anything that needs you to be alert while on this drug. Since kidney functions reduce with age, older people may experience more side effects while using this drug.

During pregnancy this drug should only be used when needed and under your physician control. Since it easily passes into breast milk you need to discuss the benefits and the risk with your doctor.


The drug interactions may not only increase your risk of side effects but also change how your medication works. You, therefore, need to have a list of all the drugs that you are currently taking and share them with your doctor. Some of the drugs that it may interact with include azathioprine, chlorpropamide, cyclosporine, mercaptopurine, ampicillin, amoxicillin, a blood thinner, and diuretic. Since this list is not complete, you also need to tell your doctor about any vitamins, over the counter drugs, and herbal medicines that you are taking.


In case you have overdosed or you are experiencing serious symptoms such as difficulty in breathing and passing out you need to call 911 immediately. You can also call the poison control center immediately. If you are staying in the US, you can call 1-800-222-1222 while in Canada call provincial poison control. You also need to avoid sharing the medicine with others.

Medical and laboratory tests such as kidney function tests, uric acid test, and complete blood count may be done once in a while to monitor your progress and check if there are any side effects. If you are taking allopurinol for kidney stones then eating a special diet may greatly help you.

In case you miss a dose take it as soon as possible but if it is near the next dose just skip and take the next dose. Do not take a double dose. Make sure you store it a room temperature and keep it away from pets and children.

Allopurinol Tablets

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