Testosterone gel belongs to a class of pharmacologic drugs called male hormonal drugs commonly defined as androgens. The testosterone gel is used to manage men who have insufficient/ inadequate or deficient of testosterone.
This is a hormone found in the body. It is the hormone that is accountable for the man-like characteristics such as broadening of shoulders, beards, male physique, and most importantly sexual libido. It is usually given to people who have a lower sexual drive.
Mode Of Action
Testosterone gel works by working in place of the normal hormone (testosterone) that is produced by the body to enhance the body's manly features.
Once you have applied the testosterone gel on the skin, the drug takes about 1 - 2 days to be absorbed by the body. Androgel reaches peak serum levels in two - six hours. The peak effect of Testosterone is seen in 3 months to 2 years. The drug is protein bound at 98% hence caution should be considered when administered with other medications. The drug then undergoes hepatic metabolism to sulfuric and glucuronic acid conjugates. These metabolites include testosterone sulfuric acid, Testosterone glucuronic conjugate, and testosterone-19-d3. The elimination half-life of the gel is usually 10 minutes to 1.8 hrs. The renal clearance of the drug is 2 liters per minute. It is later excreted in feces at 6% and predominantly in through the kidneys at 90%.
Dosage and Usage
Testosterone gel also known as Androgel, comes inside a pump bottle. It contains 60 (1.25 g doses). The hydroalcoholic gel is usually clear, no scent or odor and it is colorless. The gel contains 1% testosterone. Other non-medicinal agents that comprise the gel include sodium hydroxide, isopropyl myristate, purified water, alcohol and carbomer 980.
Testosterone Gel Side effects
Every drug has its side effects when used. Testosterone has some side effects which might be noticed and reported when they become inappropriate. They include itching sensation at the area of application, blisters, redness, burning sensation or induration at the site of application. Other effects reported though in a random manner include irritability of the bladder, acne, soreness of the breast, breasts enlargement in men, priapism, extreme malaise, headaches and dry skin among many others.
Testosterone Gel interactions
When Cyclosporine is used concomitantly with testosterone gel, it raises the levels of cyclosporine by reducing its metabolism. It also does the same to warfarin, by increasing its concentration on serum plasma. Other drugs that should be monitored closely when used together with testosterone include insulin, tinidazole, carbamazepine, and axitinib.
This gel should only be applicable to an individual for use after a confirmation of testosterone deficiency. This is important since if the drug is introduced when the person has an active secretion of testosterone, the body might lack to trigger its own and the body might be dependant on the supplementation.
Do not attempt to give testosterone gel to your friend or someone who has the same symptoms as you have. This medicine could have harmful effects when given without a prescription or proper diagnosis. Instead, inform them to consult a doctor or a pharmacist.
The common dosage of testosterone gel is 5 grams. The 5 grams contain 50 milligrams of testosterone. The gel should be applied on a daily basis one time a day. The best time to do this is after you have taken a shower. For those using testosterone pumps, your doctor might have told you how much pumping you should use when applying. Some have been prescribed as higher as 10 grams daily in a single day!
Area to apply
The area to apply the gel should be a clean area with no breakage of skin. Preferably on the abdomen or upper arms. Testosterone Gel should not be applied to the reproductive organ areas such as the vagina or penis or risk applying it on your face. Once you have applied it, allow it to dry while covering it with some clothing. Ensure you clean your palms thoroughly to avoid getting into contact with other areas when having the drug. Do not get near flammable products i.e. open flame when having the gel on your skin.
Your dosage is not the same as another person's dosage. You dosage might have been prescribed according to your illness or according to how your body has responded to the illness. The dosage might be reduced as you take it or increased when things do not seem to work. Other things that affect the dosage include other medications being taken concomitantly, the body weight of a person and other medical conditions.
When it comes to timing, ensure you take your dose at the right time. If say you are to take the drug at 7 am daily, ensure you take the drug always at that time. In case you have missed a dose and the time remaining is more than twelve hours, you can take the missed dose as soon as possible. However, if the time is less than twelve hours, you will have to wait for the next dose time and skip the missed dose. Never try to take two doses at the same time just because you missed.
Testosterone gel should be stored at room temperature, away from light and moisture. Testosterone Gel should also be kept under lock and key where children can't access.
Some people should not take this medication at all cost. These people include those that are allergic to testosterone (this entails the ingredients to this drug too), Women too should not take Testosterone Gel. It passes through breastmilk and also the placenta barrier hence should not be used by pregnant or lactating women. Those who have been diagnosed with a certain type of cancers should not also take Testosterone Gel. These cancers include breast cancer and prostate cancer.
These are the kind of drugs where you need lots of knowledge on how you can use them. You just don't buy testosterone from any site you come across. Again, one might fear or feel nervous while buying from a local dealer which might lead to low libido. Instead, buy testosterone online from sellers accredited websites and get it delivered to you. Their website has enough notes about the drug you are purchasing hence you already know what the drug entails.