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Tadalafil is a prescription drug of the class of medication known as phosphodiesterase type 5 (PDE5) inhibitors. PDE5 inhibitors stop phosphodiesterase type 5 from destroying cGMP, a substance that allows for the dilation of blood vessels. By stopping PDE5 from destroying cGMP, Tadalafil works to enhance the relaxation of muscles and blood vessels in the male reproductive system, lungs and heart to allow more flow of blood to particular body parts. Different brands of the medication (like Cialis and Adcirca) have extensive use all over the globe. A significant number of customers buy Tadalafil online.
Tadalafil is used to treat these conditions
Erectile Dysfunction (ED)
ED is a significant sexual health concern to many men. Its most common symptom is the inability to achieve an erection or failure of the penis to stay erect for long. Tadalafil is designed in a way to influence the process of erection so that a man suffering from ED can start having healthy erections, that is, full blown and long-lasting ones.
When a man gets sexually stimulated, a substance called nitric oxide (NO) is released into the penis. NO enables production of cGMP, which in turn controls the contraction and dilation of penile blood vessels. Upon stimulation, blood vessels in the penis dilate and the penis is filled with blood resulting to an erection. Another substance is later released to destroy cGMP and reverse the erection process. This substance is PDE5, and it’s what Tadalafil aims to inhibit so that the penis can be allowed to stay erect for longer.
Enlarged prostate - benign prostatic hypertrophy (BPH)
BPH is mostly experienced by men as they get older. It can cause a number of urinary problems such as difficulty urinating, frequent and urgent need to urinate, weak urine stream, and inability to empty bladder completely. In more severe cases, the affected person may be completely unable to urinate, develop a urinary tract infection or kidney problems.
Pulmonary arterial hypertension (PAH)
Under the brand names Adcirca, Tadalafil is used to reduce PAH symptoms. PDE5 is also found in the arteries making the walls of the lungs. The drug blocks the PDE5 to ensure that cGMP is not cleared quickly, so that it can relax the smooth muscles these arteries and allow for vasodilation. The transport of oxygen is increased, thus the patient is able to exercise.
Tadalafil dosage and how to use
Tadalafil tablets are available in doses of 2.5mg, 5mg, 10mg, and 20mg.
Whether you are taking Tadalafil for ED, enlarged prostate or PAH, it’s recommended that you follow the instructions on the prescription label. Tadalafil is orally (swallowed whole) and can be taken with or without food.
If using it occasionally as needed for sexual activity, an initial dose of 10mg is recommended, followed by a maintenance dose of 5 to 20 mg daily. Take a tablet of Tadalafil at least 30 minutes before sexual activity and make sure there is sexual stimulation so that an erection can occur. If you are using it for a sustained period to treat ED or BPH symptoms, start with 2.5mg taken approximately the same time of the day regardless of the timing of sexual activity.
For PAH, take 40mg once per day. Note carefully that the dosage should be taken a single time, not dividing it over the course of the day.
After knowing how the medication works for you, you can buy Tadalafil online to continue managing the symptoms of the condition you are treating.
Tadalafil side effects
If you experience any allergic reaction to Tadalafil – such as swelling of face, lips, tongue and throat, difficulty breathing or hives, get emergency medical help. You may also experience chest pain, dizziness or nausea during sex. In such a case, stop using the medication and seek medical attention.
Other possible side effects that might necessitate you calling a doctor include: if the erection lasts longer than 4 hours, sudden vision changes/loss, ringing sound in your ears, pain in your jaws or shoulders, nausea, and chest pain or pressure.
The more common and less serious side effects of using Tadalafil include: headache, upset stomach, flushing (redness, warmth, or tingly feeling), stuffy nose, and pain in the back, muscles, arms and legs.
Precautions to take when using Tadalafil
Tadalafil should not be taken by any individual who is:
- Allergic to it
- Taking other medications to treat ED, enlarged prostate, or pulmonary hypertension
- Using a nitrate drug like nitroglycerin, isosorbide mononitrate, isosorbide dinitrate, or recreational drugs such as nitrite "poppers"
If you have a kidney or liver condition, some Tadalafil may remain in your bloodstream for 2 days or so. You should particularly avoid using nitrates during this time.
Before starting using Tadalafil, make sure you inform your doctor about your medical history regarding any heart conditions, high/low blood pressure, pulmonary hypertension, liver or kidney disease, any inherited eye condition, a bleeding disorder, leukemia, multiple myeloma, or anemia, stomach ulcers, a physical deformity of the penis, or a health problem that can make sexual activity unsafe.
Alcohol consumption while using Tadalafil may temporarily decrease your blood pressure and cause dizziness and fainting. Also avoid grapefruit juice as it can increase the amount of Tadalafil in the blood.
Tadalafil should not be taken with medicines or other substances containing nitrates and alpha blockers. When combined with such substances, Tadalafil can cause a sudden drop in blood pressure and make you dizzy, or even make you pass out.
Tadalafil has been found to interact with substance like: alpha-blockers like terazosin, doxazosin, and alfuzosin; abiraterone, alprostadil, amiodarone, HIV protease inhibitors, imatinib, ivacaftor, macrolide antibiotics, etc.
An interaction does not mean that you should stop taking Tadalafil, but rather speak with your doctor on whether and how to manage the interaction. Contacting a doctor immediately you experience a serious effect is especially important if you purchase Tadalafil without prescription.
Remember this when as you decide to buy Tadalafil online
Tadalafil, being a prescription drug, should be used under a medical professional’s supervision. When you decide to buy Tadalafil online, make sure you order from a reputable online pharmacy. This is to ensure that you get genuine Tadalafil and avoid using fake drugs which can be health threatening. Buying Tadalafil without prescription is not recommended.
Tadalafil price is very competitive compared to other treatment alternatives for ED. Each online pharmacy supplying the drug has its own Tadalafil price but generally, with a few hundred bucks you get can 30 tablets and can start remedying your erectile problems or other condition. This price is quite affordable especially relative to other ED drugs that may be more expensive and their effects last only a few hours. There’s a reason why Tadalafil is referred to as “the weekend pill” – one pill gives you value for up to 36 hours meaning that it’s sufficient for an entire weekend.